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Consistently, IGF-I administration to rodents increases kidney growth, renal blood flow and glomerular filtration rate (GFR)[138, 141, 142], and similarly, GH and IGF-I also increase renal blood flow and GFR in humans[143], suggesting that IGF-I may be a physiologic regulator of renal function
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Reducing Inflammation: In autoimmune diseases, chronic inflammation is a key driver of tissue damage
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